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Targeted Allele Detail
Symbol: Sostdc1tm1Noit
Name: sclerostin domain containing 1; targeted mutation 1, Nobue Itasaki
MGI ID: MGI:3802970
Synonyms: Wise-
Gene: Sostdc1  Location: Chr12:36314169-36318452 bp, + strand  Genetic Position: Chr12, 16.82 cM, cytoband B2
Germline Transmission:  Earliest citation of germline transmission: J:137689
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe sequence in exon 1 following the translation initiation codon were replaced with an AFP and floxed neo cassette. The targeted mutation occurs in the C57BL/6 chromosome. (J:137689)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sostdc1 Mutation:  17 strains or lines available
Original:  J:137689 Shigetani Y, et al., Wise promotes coalescence of cells of neural crest and placode origins in the trigeminal region during head development. Dev Biol. 2008 Jul 15;319(2):346-58
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory