Tg(Lcn2-Tgfa)25Eps
Transgene Detail

Summary

• Symbol: Tg(Lcn2-Tgfa)25Eps
• Name: transgene insertion 25, Eric P Sandgren
• MGI ID: MGI:3802738
• Synonyms: line 1385-7, TgN(Nrl-Tgfa)25EPS
• Transgene: Tg(Lcn2-Tgfa)25Eps Location: unknown
• Alliance: Tg(Lcn2-Tgfa)25Eps page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lcn2-Tgfa)25Eps expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Tgfa (24827)

  Tgfa	(MGI:98724)

• Mutation details: The rat lipocalin 2 (also called NRL, neu-related lipocalin) promoter drives expression of a rat transforming growth factor alpha cDNA in epithelial cells of the mammary gland. (J:137737)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Lcn2-Tgfa)25Eps

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:137737 Rose-Hellekant TA, et al., Estrogen receptor-positive mammary tumorigenesis in TGFalpha transgenic mice progresses with progesterone receptor loss. Oncogene. 2007 Aug 9;26(36):5238-46
• All: 5 reference(s)