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Tg(IgkHyHEL10)1Rbr
Transgene Detail
Nomenclature
Symbol: Tg(IgkHyHEL10)1Rbr
Name: transgene insertion 1, Robert Brink
MGI ID: MGI:3800384
Synonyms: LC2 Ig
Transgene: Tg(IgkHyHEL10)1Rbr  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(IgkHyHEL10)1Rbr expresses 1 gene
 
Mutation detailsThe HyHEL10 hybridoma produces an antibody that binds hen egg lysozyme peptide (HEL) with high affinity . The transgenic construct contained the recombined gene segments of the HyHEL10 kappa light chain (Igk). Expression of the transgene was detected in B cells (J:132538)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:132538 Phan TG, et al., B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells. J Exp Med. 2003 Apr 7;197(7):845-60
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory