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Large1myd-3J
Spontaneous Allele Detail
Nomenclature
Symbol: Large1myd-3J
Name: LARGE xylosyl- and glucuronyltransferase 1; myodystrophy 3 Jackson
MGI ID: MGI:3799277
Gene: Large1  Location: Chr8:73541227-74080168 bp, - strand  Genetic Position: Chr8, 35.08 cM, cytoband C1
Muscle degeneration in Large1myd-3J/Large1myd-3J mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
Mutation
description
Allele Type:    Spontaneous
Mutation:    Undefined
 
Mutation detailsA noncomplementation test with the veils mutation demonstrated that this mutation is an allele of the Large gene.
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Large1 Mutation:  109 strains or lines available
References
Original:  J:160357 Curtain M, et al., A mouse mutation in the Large gene with muscular dystrophy and retinoschisis. MGI Direct Data Submission. 2010;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory