Apoe^{Tg(rtTA)1Gaga}
Transgenic Allele Detail

Summary

• Symbol: Apoe^{Tg(rtTA)1Gaga}
• Name: apolipoprotein E; transgene insertion 1, George A Gaitanaris
• MGI ID: MGI:3798877
• Gene: Apoe Location: Chr7:19430034-19433113 bp, - strand Genetic Position: Chr7, 9.94 cM
• Alliance: Apoe^{Tg(rtTA)1Gaga} page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:136987
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: A retroviral vector carrying a splice acceptor, STOP, IRES, rtTA, and floxed neo cassette inserted into intron 3. (J:136987)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Apoe Mutation: 145 strains or lines available

References

• Original: J:136987 Zeng H, et al., An inducible and reversible mouse genetic rescue system. PLoS Genet. 2008 May;4(5):e1000069
• All: 1 reference(s)