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Gria4tm1Mony
Targeted Allele Detail
Summary
Symbol: Gria4tm1Mony
Name: glutamate receptor, ionotropic, AMPA4 (alpha 4); targeted mutation 1, Hannah Monyer
MGI ID: MGI:3798453
Synonyms: GluA4fl, GluR-Dneo
Gene: Gria4  Location: Chr9:4417896-4796234 bp, - strand  Genetic Position: Chr9, 2.46 cM
Alliance: Gria4tm1Mony page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136763
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted upstream of exon 11 and an additional loxP site was inserted downstream of exon 11. (J:136763)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gria4 Mutation:  72 strains or lines available
References
Original:  J:136763 Fuchs EC, et al., Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior. Neuron. 2007 Feb 15;53(4):591-604
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory