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Radiation induced Allele Detail
Symbol: Del(5D5Mit388-D5Mit351)4Jcs
Name: deletion, Chr 5, John C. Schimenti 4; deletion, Chr 5, John C Schimenti 4
MGI ID: MGI:3798167
Synonyms: Del4Jcs, Hdhdf7J
Gene: Del(5D5Mit388-D5Mit351)4Jcs  Location: Chr5:33318099-37019120 bp  Genetic Position: Chr5, Syntenic
Germline Transmission:  Earliest citation of germline transmission: J:67077
Parent Cell Line:  v6.4 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S4/SvJae)F1
Allele Type:    Radiation induced
Mutation:    Intergenic deletion
  Del(5D5Mit388-D5Mit351)4Jcs involves 84 genes/genome features (Gm26605, Maea, Uvssa ...) View all
Mutation detailsTargeted insertion of thymidine kinase into the C57BL/6J derived Chromosome 5 Htt locus in the v6.4 ES cell line was followed by 400 Gy of gamma radiation, FIAU selection, and injection into the C57BL/6J blastocysts. The deletion includes the full Wolf-Hurschhorn syndrome critical region. (J:67077)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(5D5Mit388-D5Mit351)4Jcs Mutation:  0 strains or lines available
Original:  J:67077 Naf D, et al., Mouse models for the Wolf-Hirschhorn deletion syndrome. Hum Mol Genet. 2001 Jan 15;10(2):91-8
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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