Isl2^tm1Gan
Targeted Allele Detail

Summary

• Symbol: Isl2^tm1Gan
• Name: insulin related protein 2 (islet 2); targeted mutation 1, Lin Gan
• MGI ID: MGI:3797782
• Synonyms: Isl2^lacZ
• Gene: Isl2 Location: Chr9:55445956-55453464 bp, + strand Genetic Position: Chr9, 30.13 cM, cytoband C
• Alliance: Isl2^tm1Gan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:134978
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• The entire coding sequence was replaced by a LacZ gene and a neomycin resistance cassette. (J:134978)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Isl2 Mutation: 28 strains or lines available

References

• Original: J:134978 Pan L, et al., ISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cells. Development. 2008 Jun;135(11):1981-90
• All: 1 reference(s)