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Krt19tm1(cre/ERT)Ggu
Targeted Allele Detail
Nomenclature
Symbol: Krt19tm1(cre/ERT)Ggu
Name: keratin 19; targeted mutation 1, Guoqiang Gu
MGI ID: MGI:3797107
Synonyms: CK19CreERT, K19CreER, Krt19-CreERT, Krt19tm1(cre/ESR1)Ggu
Gene: Krt19  Location: Chr11:100140810-100145926 bp, - strand  Genetic Position: Chr11, 63.42 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136694
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsAn inducible cre/ESR1 fusion gene followed by an frt-flanked neo cassette was inserted upstream of the translation initiation codon. Cre expression is restricted to epithelial cells in multiple endodermal organs (pancreatic ducts, hepatic ducts, stomach and intestine). (J:136694)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Krt19     Summary of all recombinase alleles driven by Krt19. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Krt19 Mutation:  2 strains or lines available
References
Original:  J:136694 Means AL, et al., A CK19(CreERT) knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs. Genesis. 2008 Jun;46(6):318-23
All:  28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/07/2019
MGI 6.14
The Jackson Laboratory