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Adgrg1tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Adgrg1tm1Lex
Name: adhesion G protein-coupled receptor G1; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3796624
Synonyms: Gpr56-KO
Gene: Adgrg1  Location: Chr8:94974756-95014208 bp, + strand  Genetic Position: Chr8, 47.12 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136385
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3 were replaced with a lacZ/neo cassette. The absence of protein product was confirmed by western blot anlaysis on brain extracts. This is a null allele and a reporter allele. (J:136385)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 24 assay results
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Adgrg1 Mutation:  19 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:136385 Li S, et al., GPR56 regulates pial basement membrane integrity and cortical lamination. J Neurosci. 2008 May 28;28(22):5817-26
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory