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Cplx3tm1Rmnd
Targeted Allele Detail
Nomenclature
Symbol: Cplx3tm1Rmnd
Name: complexin 3; targeted mutation 1, Christian Rosenmund
MGI ID: MGI:3796622
Gene: Cplx3  Location: Chr9:57600019-57606281 bp, - strand  Genetic Position: Chr9, 31.11 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136393
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe first coding exon was replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis on brain extracts. (J:136393)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cplx3 Mutation:  5 strains or lines available
References
Original:  J:136393 Xue M, et al., Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system. Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7875-80
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory