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Col7a1tm1Lbt
Targeted Allele Detail
Nomenclature
Symbol: Col7a1tm1Lbt
Name: collagen, type VII, alpha 1; targeted mutation 1, Leena Bruckner-Tuderman
MGI ID: MGI:3796248
Synonyms: Col7a1flneo
Gene: Col7a1  Location: Chr9:108953586-108984875 bp, + strand  Genetic Position: Chr9, 59.63 cM
Col7a1tm1Lbt/Col7a1tm1Lbt mice develop blisters early after birth

Show the 6 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136145
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, Hypomorph)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Col7a1 Mutation:  2 strains or lines available
References
Original:  J:136145 Fritsch A, et al., A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fibroblast therapy. J Clin Invest. 2008 May;118(5):1669-79
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory