Msx2tm1Yvla
Targeted Allele Detail
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Symbol: |
Msx2tm1Yvla |
Name: |
msh homeobox 2; targeted mutation 1, Yvan Lallemand |
MGI ID: |
MGI:3795774 |
Synonyms: |
Msx2flox, Msx2Flox-GFP |
Gene: |
Msx2 Location: Chr13:53620917-53626816 bp, - strand Genetic Position: Chr13, 27.84 cM
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Alliance: |
Msx2tm1Yvla page
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Germline Transmission: |
Earliest citation of germline transmission:
J:136241
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Parent Cell Line: |
CK35 (ES Cell)
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Strain of Origin: |
129S2/SvPas
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Allele Type: |
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Targeted (Conditional ready, No functional change, Reporter) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted into exon 1 upstream of the initiation codon, and an frt-flanked neomycin resistance cassette with a 3' loxP site, followed by an internal ribosomal entry site (IRES) and the coding sequence for green fluorescent protein (GFP), was inserted into the second exon downstream of the stop codon. The neo cassette was removed by germ line, flp-mediated recombination. This is a conditional knockout (floxed) allele and a reporter allele.
(J:136241)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Msx2 Mutation: |
23 strains or lines available
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Original: |
J:136241 Bensoussan V, et al., Generation of an Msx2-GFP conditional null allele. Genesis. 2008 May;46(5):276-82 |
All: |
7 reference(s) |
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