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Msx2tm1Yvla
Targeted Allele Detail
Nomenclature
Symbol: Msx2tm1Yvla
Name: msh homeobox 2; targeted mutation 1, Yvan Lallemand
MGI ID: MGI:3795774
Synonyms: Msx2flox, Msx2Flox-GFP
Gene: Msx2  Location: Chr13:53466884-53473074 bp, - strand  Genetic Position: Chr13, 27.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136241
Parent Cell Line:  CK35 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted into exon 1 upstream of the initiation codon and an frt-flanked neo cassette with a 3' loxP site followed by an IRES-GFP cassette was inserted into the second exon downstream of the stop codon. The neo cassette was removed by germ line, flp-mediated recombination. This is a floxed allele and a reporter allele. (J:136241)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Msx2 Mutation:  13 strains or lines available
References
Original:  J:136241 Bensoussan V, et al., Generation of an Msx2-GFP conditional null allele. Genesis. 2008 May;46(5):276-82
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory