Nmur1^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Nmur1^tm1Lex
• Name: neuromedin U receptor 1; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3795273
• Gene: Nmur1 Location: Chr1:86313964-86317083 bp, - strand Genetic Position: Chr1, 43.94 cM, cytoband C5
• Alliance: Nmur1^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:135815
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Nucleotides 4117 to 4868 were replaced with a neo cassette. The absence of transcript was confirmed by RT-PCR on uterus and fundus extracts. (J:135815)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nmur1 Mutation: 20 strains or lines available

References

• Original: J:135815 Prendergast CE, et al., Species-dependent smooth muscle contraction to Neuromedin U and determination of the receptor subtypes mediating contraction using NMU1 receptor knockout mice. Br J Pharmacol. 2006 Apr;147(8):886-96
• All: 1 reference(s)