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Ddx20tm1Yosa
Targeted Allele Detail
Nomenclature
Symbol: Ddx20tm1Yosa
Name: DEAD box helicase 20; targeted mutation 1, Yoel Sadovsky
MGI ID: MGI:3795148
Synonyms: Dp103-
Gene: Ddx20  Location: Chr3:105678270-105687574 bp, - strand  Genetic Position: Chr3, 46.43 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136021
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 1 and all of intron 1 were replaced with a myc-tagged EGFP followed by a floxed neo cassette. The absence of protein product was confirmed by immunohistochemistry. This is a null allele and a reporter allele. (J:136021)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ddx20 Mutation:  21 strains or lines available
References
Original:  J:136021 Mouillet JF, et al., DEAD-box protein-103 (DP103, Ddx20) is essential for early embryonic development and modulates ovarian morphology and function. Endocrinology. 2008 May;149(5):2168-75
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory