About   Help   FAQ
Tg(LCR-HBA2,LCR-HBB)11Cos
Transgene Detail
Nomenclature
Symbol: Tg(LCR-HBA2,LCR-HBB)11Cos
Name: transgene insertion 11, Frank Costantini
MGI ID: MGI:3794861
Synonyms: alphaHbetaS, NY1DD, NY-S
Transgene: Tg(LCR-HBA2,LCR-HBB)11Cos  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(LCR-HBA2,LCR-HBB)11Cos expresses 3 genes
 
Mutation detailsConstructs expressing the human alpha globin 2 gene from the locus control region of the human beta globin gene and the human beta globin gene also from the human locus control region were coinjected to create a line of mice with cointegrated transgenes. Transgene expression is noted in red blood cells. (J:129579)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:129579 Fabry ME, et al., High expression of human beta S- and alpha-globins in transgenic mice: hemoglobin composition and hematological consequences. Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):12150-4
All:  27 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory