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Gene trapped Allele Detail
Symbol: Akt1Gt1Pnt
Name: thymoma viral proto-oncogene 1; gene trap 1, Philip N Tsichlis
MGI ID: MGI:3794786
Synonyms: Akt1-
Gene: Akt1  Location: Chr12:112653821-112674884 bp, - strand  Genetic Position: Chr12, 61.2 cM, cytoband F1-F2
Germline Transmission:  Earliest citation of germline transmission: J:135903
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Gene trapped (Null/knockout)
Mutation:    Insertion of gene trap vector
Mutation detailsA retrovirus vector integrated 3 bp upstream of the initiation methionine codon. The absence of protein product was confirmed by western blot analysis on mammary tissue extracts. (J:135903)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Akt1 Mutation:  15 strains or lines available
Original:  J:135903 Mao C, et al., Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition. J Immunol. 2007 May 1;178(9):5443-53
All:  7 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.04
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