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Akt1Gt1Pnt
Gene trapped Allele Detail
Summary
Symbol: Akt1Gt1Pnt
Name: thymoma viral proto-oncogene 1; gene trap 1, Philip N Tsichlis
MGI ID: MGI:3794786
Synonyms: Akt1-
Gene: Akt1  Location: Chr12:112620260-112641266 bp, - strand  Genetic Position: Chr12, 61.2 cM, cytoband F1-F2
Alliance: Akt1Gt1Pnt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:135903
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Gene trapped (Null/knockout)
Mutation:    Insertion of gene trap vector
 
Mutation detailsA retrovirus vector integrated 3 bp upstream of the initiation methionine codon. The absence of protein product was confirmed by western blot analysis on mammary tissue extracts. (J:135903)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Akt1Gt1Pnt
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Akt1 Mutation:  34 strains or lines available
References
Original:  J:135903 Mao C, et al., Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition. J Immunol. 2007 May 1;178(9):5443-53
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory