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Tg(HBV-HCV)Kko
Transgene Detail
Nomenclature
Symbol: Tg(HBV-HCV)Kko
Name: transgene insertion, Kazuhiko Koike
MGI ID: MGI:3794557
Transgene: Tg(HBV-HCV)Kko  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6NJcl
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA 0.6 kb fragment involving the HCV core protein was cloned downstream of HBV regulatory elements. 3-4 copies of the transgene were found in the original C21 founder. Transgene expression was detected in the liver, but not in the brain, salivary glands, lung, intestines, spleen or kidney. (J:94426)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:94426 Moriya K, et al., Hepatitis C virus core protein induces hepatic steatosis in transgenic mice. J Gen Virol. 1997 Jul;78(Pt 7):1527-31
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory