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Sfrp5tm1Aksh
Targeted Allele Detail
Nomenclature
Symbol: Sfrp5tm1Aksh
Name: secreted frizzled-related sequence protein 5; targeted mutation 1, Akihiko Shimono
MGI ID: MGI:3793862
Gene: Sfrp5  Location: Chr19:42197971-42202252 bp, - strand  Genetic Position: Chr19, 35.93 cM, cytoband D1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:135313
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe 5' coding region in the first exon encoding the cystein rich domain was replaced with a neo cassette followed by and IRES-YFP variant with multiple stop codons. (J:135313)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sfrp5 Mutation:  4 strains or lines available
References
Original:  J:135313 Satoh W, et al., Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse. Genesis. 2008 Feb;46(2):92-103
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory