About   Help   FAQ
Tg(Myh6-TNNT2*I79N)8Jdp
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-TNNT2*I79N)8Jdp
Name: transgene insertion 8, James D Potter
MGI ID: MGI:3793476
Synonyms: HCTnT-I79N, Tg-I79N
Transgene: Tg(Myh6-TNNT2*I79N)8Jdp  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-TNNT2*I79N)8Jdp expresses 1 gene
 
Mutation detailsThe transgene construct consists of about 5.5 kilobases of the mouse alpha-myosin heavy chain promoter, including the first 2 exons and part of the third, followed by the human TNNT2 cDNA (876 base pairs) modified to express a I79N mutation, and a 630-base pair 3'-untranslated region from the human growth hormone transcript. (J:67284)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:67284 Miller T, et al., Abnormal contractile function in transgenic mice expressing a familial hypertrophic cardiomyopathy-linked troponin T (I79N) mutation. J Biol Chem. 2001 Feb 9;276(6):3743-55
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/04/2019
MGI 6.14
The Jackson Laboratory