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Klrk1tm1Dhr
Targeted Allele Detail
Nomenclature
Symbol: Klrk1tm1Dhr
Name: killer cell lectin-like receptor subfamily K, member 1; targeted mutation 1, David H Raulet
MGI ID: MGI:3790957
Synonyms: NKG2D-
Gene: Klrk1  Location: Chr6:129610323-129623864 bp, - strand  Genetic Position: Chr6, 63.44 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:134509
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Klrk1 Mutation:  6 strains or lines available
References
Original:  J:134509 Guerra N, et al., NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity. 2008 Apr;28(4):571-80
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory