Fgf16tm1.1(cre)Sms
Targeted Allele Detail
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Symbol: |
Fgf16tm1.1(cre)Sms |
Name: |
fibroblast growth factor 16; targeted mutation 1.1, Suzanne L Monsour |
MGI ID: |
MGI:3790784 |
Synonyms: |
Fgf16IRESCre |
Gene: |
Fgf16 Location: ChrX:104807885-104818545 bp, + strand Genetic Position: ChrX, 47.2 cM, cytoband C3
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Alliance: |
Fgf16tm1.1(cre)Sms page
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Fgf16tm1.1(cre)Sms expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: Cre recombinase is expressed from this allele under control of the endogenous Fgf16 promoter in the developing cristae and spiral prominence epithelial precursors of the inner ear. The Cre recombinase coding sequence, preceded by an internal ribosomal entry site (IRES) and followed by a single frt site (marking the site of excision of a frt-flanked neomycin resistance cassette), interrupts the first exon of Fgf16 so that codon 63 is disrupted.
(J:139718)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Fgf16
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Fgf16 Mutation: |
4 strains or lines available
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This allele was derived from Fgf16tm1(cre)Sms, mutants for which have been characterized phenotypically, by crossing mice bearing that allele with FLPe-expressing animals.
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Original: |
J:139718 Hatch EP, et al., Fgf16(IRESCre) mice: a tool to inactivate genes expressed in inner ear cristae and spiral prominence epithelium. Dev Dyn. 2009 Feb;238(2):358-66 |
All: |
2 reference(s) |
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