About   Help   FAQ
Hbbtm3(HBG1,HBB)Tow
Targeted Allele Detail
Nomenclature
Symbol: Hbbtm3(HBG1,HBB)Tow
Name: hemoglobin beta chain complex; targeted mutation 3, Timothy Townes
MGI ID: MGI:3790756
Synonyms: -383 gamma-betaA, Hbbtm3(HBB)Tow
Gene: Hbb  Location: unknown  Genetic Position: Chr7, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:134980
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (knock-in)
Mutations:    Insertion, Intergenic deletion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hbb Mutation:  20 strains or lines available
Notes
Mice heterozgyote for this and the Hbb allele, and homozygous for Hbatm1(HBA)Tow allele Show Phenotypic Similarity to Human Syndrome: Beta Thalassemia Minor (J:148521)

References
Original:  J:134980 Wu LC, et al., Correction of sickle cell disease by homologous recombination in embryonic stem cells. Blood. 2006 Aug 15;108(4):1183-8
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/08/2014
MGI 5.17
The Jackson Laboratory