About   Help   FAQ
Hbatm1(HBA)Tow
Targeted Allele Detail
Nomenclature
Symbol: Hbatm1(HBA)Tow
Name: hemoglobin alpha chain complex; targeted mutation 1, Timothy Townes
MGI ID: MGI:3790755
Synonyms: HbA, Hbahalpha
Gene: Hba  Location: unknown  Genetic Position: Chr11, cytoband A
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:134980
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Humanized sequence, Inserted expressed sequence)
Mutations:    Insertion, Intragenic deletion
  Hbatm1(HBA)Tow involves 1 genes/genome features (Hba) View all
    The complex was replaced with human HBA. Details will be described elsewhere. (J:134980)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Hba Mutation:  9 strains or lines available
References
Original:  J:134980 Wu LC, et al., Correction of sickle cell disease by homologous recombination in embryonic stem cells. Blood. 2006 Aug 15;108(4):1183-8
All:  44 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/16/2021
MGI 6.17
The Jackson Laboratory