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In(10)17Rk
Chemically induced Allele Detail
Nomenclature
Symbol: In(10)17Rk
Name: inversion, Chr 10, Roderick 17
MGI ID: MGI:3790439
Synonyms: Hmga2pg-J, In17Rk, pygmy Jackson
Gene: In(10)17Rk  Location: unknown  Genetic Position: Chr10, Syntenic
Mutation
origin
Strain of Origin:  DBA/2J
Mutation
description
Allele Type:    Chemically induced (other)
Mutation:    Inversion
  In(10)17Rk involves 1781 genes/genome features (Gm17567, 1700026H06Rik, B930046M08Rik ...) View all
 
Mutation detailsThis triethylene melamine-induced inversion of approximately 60 cM causes a homozygous pygmy phenotype, it is allelic by complementation test with Hmga2pg, the distal breakpoint is in intron 3 of Hmga2, and the proximal breakpoint is in intron 2 of Txlnb. A 3.7 kb fusion transcript of Hmga2 exons 4 and 5 and Txlnb exons 1 and 2 is produced. No other Txlnb transcript was found by northern blot of homozygous heart or femur. (J:28571, J:43743, J:74548)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any In(10)17Rk Mutation:  1 strain or line available
References
Original:  J:23389 Roderick TH, Using inversions to detect and study recessive lethals and detrimentals in mice, in Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk. 1983:135-67.
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory