About   Help   FAQ
Gbx2tm1.2Alj
Targeted Allele Detail
Summary
Symbol: Gbx2tm1.2Alj
Name: gastrulation brain homeobox 2; targeted mutation 1.2, Alexandra L Joyner
MGI ID: MGI:3790113
Synonyms: Gbx2deltahd, Gbx2n
Gene: Gbx2  Location: Chr1:89855684-89858898 bp, - strand  Genetic Position: Chr1, 45.06 cM, cytoband C5-E1
Alliance: Gbx2tm1.2Alj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79431
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsTransgenic CMV-cre mice are crossed to Gbx2tm1.1Alj heterozygotes to delete most of exon 2 producing the Gbx2tm1.2Alj/+ allele. (J:79431)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gbx2 Mutation:  27 strains or lines available
References
Original:  J:79431 Li JY, et al., Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer. Neuron. 2002 Sep 26;36(1):31-43
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory