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Gbx2tm1.2Alj
Targeted Allele Detail
Nomenclature
Symbol: Gbx2tm1.2Alj
Name: gastrulation brain homeobox 2; targeted mutation 1.2, Alexandra L Joyner
MGI ID: MGI:3790113
Synonyms: Gbx2deltahd, Gbx2n
Gene: Gbx2  Location: Chr1:89927956-89931179 bp, - strand  Genetic Position: Chr1, 45.06 cM, cytoband C5-E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79431
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsTransgenic CMV-cre mice are crossed to Gbx2tm1.1Alj heterozygotes to delete most of exon 2 producing the Gbx2tm1.2Alj/+ allele. (J:79431)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gbx2 Mutation:  9 strains or lines available
References
Original:  J:79431 Li JY, et al., Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer. Neuron. 2002 Sep 26;36(1):31-43
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory