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Tgfbr2tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Tgfbr2tm1Dgen
Name: transforming growth factor, beta receptor II; targeted mutation 1, Deltagen
MGI ID: MGI:3785874
Synonyms: Tgfbr2-
Gene: Tgfbr2  Location: Chr9:116087695-116175363 bp, - strand  Genetic Position: Chr9, 68.39 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99304
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
    106 bp of the open reading frame in exon 5 was replaced with an IRES-lacZ-neo cassette. (J:99304)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tgfbr2 Mutation:  7 strains or lines available
References
Original:  J:99304 Schadt EE, et al., An integrative genomics approach to infer causal associations between gene expression and disease. Nat Genet. 2005 Jul;37(7):710-7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory