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Tg(CAG-Has2)99Nita
Transgene Detail
Nomenclature
Symbol: Tg(CAG-Has2)99Nita
Name: transgene insertion 99, Naoki Itano
MGI ID: MGI:3785859
Synonyms: CAG-Neo-Has2, HA-99, Has2 cTg
Transgene: Tg(CAG-Has2)99Nita  Location: unknown  
Transgene
origin
Strain of Origin:  BALB/cCrSlc
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-Has2)99Nita expresses 1 gene
 
Mutation detailsThe CAG promoter (chicken beta actin promoter) was used to drive ubiquitous expression of a flag-tagged Has2 cDNA preceded by a floxed neo cassette with a polyadenylation sequence. Cre-mediated recombination is required to remove the neo cassette and allow for Has2 expression. Seven lines were established with line HA-99 examined further. (J:118655)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:118655 Koyama H, et al., Hyperproduction of Hyaluronan in Neu-Induced Mammary Tumor Accelerates Angiogenesis through Stromal Cell Recruitment: Possible Involvement of Versican/PG-M. Am J Pathol. 2007 Mar;170(3):1086-99
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory