Tg(Ins2-E3*734)4Dvs
Transgene Detail

Summary

• Symbol: Tg(Ins2-E3*734)4Dvs
• Name: transgene insertion 4, David V Serreze
• MGI ID: MGI:3785757
• Transgene: Tg(Ins2-E3*734)4Dvs Location: unknown
• Alliance: Tg(Ins2-E3*734)4Dvs page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The rat insulin promoter was placed upstream of the adenovirus early region 3 (E3) sequences with two point mutations inthe first two methionines of the 11.6K open reading frame. (J:106340)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:106340 Pierce MA, et al., Adenovirus early region 3 transgenes expressed in beta cells prevent autoimmune diabetes in nonobese diabetic mice: effects of deleting the adenovirus death protein 11.6K. J Virol. 2005 Jan;79(1):619-21
• All: 1 reference(s)