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Tg(Ins2-E3*734)4Dvs
Transgene Detail
Nomenclature
Symbol: Tg(Ins2-E3*734)4Dvs
Name: transgene insertion 4, David V Serreze
MGI ID: MGI:3785757
Transgene: Tg(Ins2-E3*734)4Dvs  Location: unknown  
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe rat insulin promoter was placed upstream of the adenovirus early region 3 (E3) sequences with two point mutations inthe first two methionines of the 11.6K open reading frame. (J:106340)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:106340 Pierce MA, et al., Adenovirus early region 3 transgenes expressed in beta cells prevent autoimmune diabetes in nonobese diabetic mice: effects of deleting the adenovirus death protein 11.6K. J Virol. 2005 Jan;79(1):619-21
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory