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Tg(Jam2-cre/ERT2)2Jrs
Transgene Detail
Nomenclature
Symbol: Tg(Jam2-cre/ERT2)2Jrs
Name: transgene insertion 2, Joshua R Sanes
MGI ID: MGI:3785734
Synonyms: JAM-B-CreER, JAMB-CreER, Tg(Jam2-cre/ESR1)1Jrs
Transgene: Tg(Jam2-cre/ERT2)2Jrs  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsA tamoxifen inducible form of cre recombinase and a frt-lanked neomycin selection cassette was put under the control of Jam2 promoter sequences. Transgenic founder mice were crossed with Flpe transgenic mice to remove the neomycin selection cassette. Expression of Cre was confirmed in a subset of retinal neurons upon tamoxifen induction. (J:134167)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Jam2     Summary of all recombinase alleles driven by Jam2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:134167 Kim IJ, et al., Molecular identification of a retinal cell type that responds to upward motion. Nature. 2008 Mar 27;452(7186):478-82
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory