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Transgene Detail
Symbol: Tg(Ttn-Ighmbp2)108Cx
Name: transgene insertion 108, Gregory A Cox
MGI ID: MGI:3785079
Synonyms: TgMI
Transgene: Tg(Ttn-Ighmbp2)108Cx  Location: unknown  
Strain of Origin:  C57BL/6J
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(Ttn-Ighmbp2)108Cx expresses 1 gene
Mutation detailsa cDNA sequence encoding the full mouse Ighmbp2 was placed under the control of a modified 5.87 kb mouse genomic fragment containing the Ttn promoter, non-coding Ttn exon 1, intron 1, and 30 base pairs of Ttn exon 2 lacking the start codon. Transgene expression was limited to the heart and skeletal muscles as confirmed by RT-PCR expression using Ighmbp2 exon 1. (J:102748)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:102748 Maddatu TP, et al., Dilated cardiomyopathy in the nmd mouse: transgenic rescue and QTLs that improve cardiac function and survival. Hum Mol Genet. 2005 Nov 1;14(21):3179-89
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.16
The Jackson Laboratory