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Pscatm1Witt
Targeted Allele Detail
Nomenclature
Symbol: Pscatm1Witt
Name: prostate stem cell antigen; targeted mutation 1, Owen N Witte
MGI ID: MGI:3784994
Gene: Psca  Location: Chr15:74714839-74717069 bp, + strand  Genetic Position: Chr15, 34.26 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:133908
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAll of exon 2 and a portion of exon 3 were replaced with a neo cassette. The absence of transcript was confirmed by RT-PCR from prostate and bladder extracts. (J:133908)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Psca Mutation:  2 strains or lines available
References
Original:  J:133908 Moore ML, et al., Deletion of PSCA increases metastasis of TRAMP-induced prostate tumors without altering primary tumor formation. Prostate. 2008 Feb 1;68(2):139-51
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/17/2015
MGI 5.21
The Jackson Laboratory