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LeprDb-2Btlr
Chemically induced Allele Detail
Nomenclature
Symbol: LeprDb-2Btlr
Name: leptin receptor; diabetes 2 Bruce Beutler
MGI ID: MGI:3784992
Synonyms: cherub, Leprm2Btlr
Gene: Lepr  Location: Chr4:101717404-101815352 bp, + strand  Genetic Position: Chr4, 46.96 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation details
Inheritance:    Semidominant
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lepr Mutation:  28 strains or lines available
Notes
Mice with this mutation were not checked for hyperglycemia. J:133633

References
Original:  J:133633 Xiao N, et al., Cherub is an allele of lepr (leptin receptor) associated with massive obesity and infertility. MGI Direct Data Submission. 2008;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory