Tg(Krt15-cre/ERT2)1Johu
Transgene Detail

Summary

• Symbol: Tg(Krt15-cre/ERT2)1Johu
• Name: transgene insertion 1, Joerg Huelsken
• MGI ID: MGI:3784521
• Synonyms: K15-creER^T2
• Transgene: Tg(Krt15-cre/ERT2)1Johu Location: unknown
• Alliance: Tg(Krt15-cre/ERT2)1Johu page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Krt15-cre/ERT2)1Johu expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Krt15

• Mutation details: 5 Kb of the Kr15 promoter was used to drive hair follicle bulge stem cell specific expression of a cre/ESR1 (ERT2) fusion. Cre expression is tamoxifen inducible. No line information was provided. (J:133779)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Krt15 (species not specified) Summary of all recombinase alleles driven by Krt15. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:133779 Malanchi I, et al., Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling. Nature. 2008 Apr 3;452(7187):650-3
• All: 1 reference(s)