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Pbx1tm2.1Mlc
Targeted Allele Detail
Nomenclature
Symbol: Pbx1tm2.1Mlc
Name: pre B cell leukemia homeobox 1; targeted mutation 2.1, Micheal L Cleary
MGI ID: MGI:3783740
Gene: Pbx1  Location: Chr1:168119364-168432270 bp, - strand  Genetic Position: Chr1, 75.95 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:132963
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCre mediated recombination of Pbx1tm2Mlc resulted in deletion of exon 3. (J:132963)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pbx1 Mutation:  19 strains or lines available
References
Original:  J:132963 Sanyal M, et al., B-cell development fails in the absence of the Pbx1 proto-oncogene. Blood. 2007 May 15;109(10):4191-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory