Ret^tm2.1Heno
Targeted Allele Detail

Summary

• Symbol: Ret^tm2.1Heno
• Name: ret proto-oncogene; targeted mutation 2.1, Hideki Enomoto
• MGI ID: MGI:3777556
• Synonyms: Ret^CFP
• Gene: Ret Location: Chr6:118128706-118174679 bp, - strand Genetic Position: Chr6, 55.86 cM, cytoband E3-F1
• Alliance: Ret^tm2.1Heno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132854
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: Germ-line, cre-mediated recombination was used to remove the human RET cassette leaving the CFP cassette intact. This is also a null allele. (J:132854)

Disease models

Expression

In Mice Carrying this Mutation:	41 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ret Mutation: 53 strains or lines available

References

• Original: J:132854 Gould TW, et al., The neurotrophic effects of glial cell line-derived neurotrophic factor on spinal motoneurons are restricted to fusimotor subtypes. J Neurosci. 2008 Feb 27;28(9):2131-46
• All: 9 reference(s)