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Targeted Allele Detail
Symbol: Dab1tm1.1Bwh
Name: disabled 1; targeted mutation 1.1, Brian W Howell
MGI ID: MGI:3777253
Synonyms: Dab1exKIneo
Gene: Dab1  Location: Chr4:103619359-104744844 bp, + strand  Genetic Position: Chr4, 47.79 cM
Germline Transmission:  Earliest citation of germline transmission: J:132599
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThe coding region of amino acids 23 through 555 was removed by germ-line, cre-mediated recombination. Authors state that this is a null allele based on the phenotypes generated in homozygous mice. (J:132599)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dab1 Mutation:  53 strains or lines available
Original:  J:132599 Pramatarova A, et al., A genetic interaction between the APP and Dab1 genes influences brain development. Mol Cell Neurosci. 2008 Jan;37(1):178-86
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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