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Srrttm1Bfk
Targeted Allele Detail
Nomenclature
Symbol: Srrttm1Bfk
Name: serrate RNA effector molecule homolog (Arabidopsis); targeted mutation 1, Ben F Koop
MGI ID: MGI:3777245
Gene: Srrt  Location: Chr5:137295711-137307666 bp, - strand  Genetic Position: Chr5, 76.33 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:132672
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA fragment including the proximal promoter and exons 1 - 3 was replaced with floxed PGK-neo cassette via homologous recombination. The neo cassette was removed via in vivo Cre mediated recombination. (J:132672)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Srrt Mutation:  31 strains or lines available
References
Original:  J:132672 Wilson MD, et al., ARS2 is a conserved eukaryotic gene essential for early mammalian development. Mol Cell Biol. 2008 Mar;28(5):1503-14
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory