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Zbp1tm1Aki
Targeted Allele Detail
Nomenclature
Symbol: Zbp1tm1Aki
Name: Z-DNA binding protein 1; targeted mutation 1, Shizuo Akira
MGI ID: MGI:3776827
Synonyms: DAI-
Gene: Zbp1  Location: Chr2:173206612-173218923 bp, - strand  Genetic Position: Chr2, 95.83 cM, cytoband H3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:132662
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 2 and all of exon 3 were replaced with a neomycin resistance cassette. A lack of gene expression was confirmed by northern blot analysis of embryonic fibroblasts isolated from homozygotes. (J:132662)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zbp1 Mutation:  11 strains or lines available
References
Original:  J:132662 Ishii KJ, et al., TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature. 2008 Feb 7;451(7179):725-9
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory