Tg(KLKB1-cre/ERT2)1Pcn
Transgene Detail

Summary

• Symbol: Tg(KLKB1-cre/ERT2)1Pcn
• Name: transgene insertion 1, Pierre Chambon
• MGI ID: MGI:3775927
• Synonyms: PSA-Cre-ER^T2, Tg(KLK30-creESR1)1Pcn
• Transgene: Tg(KLKB1-cre/ERT2)1Pcn Location: unknown
• Alliance: Tg(KLKB1-cre/ERT2)1Pcn page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(KLKB1-cre/ERT2)1Pcn expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  KLKB1 (3818)

  Klkb1

  (MGI:102849)

• The human KLKB1 was used to drive the expression of a cre/ERT2 cassette in the prostatic epithelium. (J:132170)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	KLKB1 (human) Summary of all recombinase alleles driven by KLKB1. Alliance human KLKB1 gene page

Tumor Data

List all tumor models in MMHCdb carrying Tg(KLKB1-cre/ERT2)1Pcn

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:132170 Ratnacaram CK, et al., Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2521-6
• All: 8 reference(s)