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Targeted Allele Detail
Symbol: Esr2tm1.1Pcn
Name: estrogen receptor 2 (beta); targeted mutation 1.1, Pierre Chambon
MGI ID: MGI:3775924
Synonyms: ERbetaL2, ERbetaSTL2
Gene: Esr2  Location: Chr12:76120419-76177259 bp, - strand  Genetic Position: Chr12, 33.52 cM, cytoband D1-D3
Germline Transmission:  Earliest citation of germline transmission: J:132171
Parent Cell Line:  H1 (ES Cell)
Strain of Origin:  129S2/SvPas
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsGerm-line, cre-mediated recombination was used to remove the neo cassette located downstream of exon 3 leaving exon 3 floxed. (J:132171)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Esr2 Mutation:  25 strains or lines available
Original:  J:132171 Antal MC, et al., Sterility and absence of histopathological defects in nonreproductive organs of a mouse ERbeta-null mutant. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2433-8
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory