Tg(Postn-cre)1Sjc
Transgene Detail

Summary

• Symbol: Tg(Postn-cre)1Sjc
• Name: transgene insertion 1, Simon J Conway
• MGI ID: MGI:3775923
• Synonyms: 3.9Periostin-Cre, Postn^Cre/eGFP
• Transgene: Tg(Postn-cre)1Sjc Location: unknown
• Alliance: Tg(Postn-cre)1Sjc page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Postn-cre)1Sjc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Postn (MGI:1926321)

• Mutation details: This transgene consists of 3.9 kb of the mouse periostin promoter (up to the translation start codon) driving expression of a cre/EGFP fusion gene. Cre expression is seen in cells of the Schwann cell lineage after E11. The EGFP gene is not functional, either in vivo or in vitro. (J:131914)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Postn (mouse) Summary of all recombinase alleles driven by Postn. Comparative matrix view of recombinase activities Alliance mouse Postn gene page

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:131914 Joseph NM, et al., The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells. Cancer Cell. 2008 Feb;13(2):129-40
• All: 27 reference(s)