About   Help   FAQ
Aplntm1Ntak
Targeted Allele Detail
Nomenclature
Symbol: Aplntm1Ntak
Name: apelin; targeted mutation 1, Nobuyuki Takakura
MGI ID: MGI:3775290
Gene: Apln  Location: ChrX:48025146-48034853 bp, - strand  Genetic Position: ChrX, 25.48 cM, cytoband A3.2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:131824
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 3.1 kb fragment including all of exon 2 was replaced with a neo cassette via homologous recombination. (J:131824)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Apln Mutation:  7 strains or lines available
References
Original:  J:131824 Kidoya H, et al., Spatial and temporal role of the apelin/APJ system in the caliber size regulation of blood vessels during angiogenesis. EMBO J. 2008 Feb 6;27(3):522-34
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/12/2019
MGI 6.14
The Jackson Laboratory