About   Help   FAQ
Notch1tm2.1Pst
Targeted Allele Detail
Nomenclature
Symbol: Notch1tm2.1Pst
Name: notch 1; targeted mutation 2.1, Pamela Stanley
MGI ID: MGI:3774554
Synonyms: Notch1lbd
Gene: Notch1  Location: Chr2:26457903-26516663 bp, - strand  Genetic Position: Chr2, 18.91 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:131563
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exons 6 through 8 were deleted by germ-line cre-meditated recombination. (J:131563)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Notch1 Mutation:  61 strains or lines available
References
Original:  J:131563 Ge C, et al., The O-fucose glycan in the ligand-binding domain of Notch1 regulates embryogenesis and T cell development. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1539-44
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/23/2017
MGI 6.09
The Jackson Laboratory