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Targeted Allele Detail
Symbol: Flcntm1Baba
Name: folliculin; targeted mutation 1, Masaya Baba
MGI ID: MGI:3774414
Synonyms: BHDf, Flcntm1Lss
Gene: Flcn  Location: Chr11:59791408-59810016 bp, - strand  Genetic Position: Chr11, 37.79 cM
Germline Transmission:  Earliest citation of germline transmission: J:130978
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA frt-flanked and floxed neo cassette was inserted into inton 6 and an additional loxP site was inserted into intron 7. The neo cassette was removed by germ-line, flp-mediated recombination to yield a floxed exon 7. (J:130978)
View phenotypes for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Flcn Mutation:  10 strains or lines available
Original:  J:130978 Baba M, et al., Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys. J Natl Cancer Inst. 2008 Jan 16;100(2):140-54
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory