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Eomestm1.1Rob
Targeted Allele Detail
Summary
Symbol: Eomestm1.1Rob
Name: eomesodermin; targeted mutation 1.1, Elizabeth J Robertson
MGI ID: MGI:3774028
Synonyms: EomesN
Gene: Eomes  Location: Chr9:118307259-118315176 bp, + strand  Genetic Position: Chr9, 70.21 cM, cytoband F3
Alliance: Eomestm1.1Rob page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:131055
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsHeterozygous Eomestm1Rob males were crossed to females expressing a cre transgene that is active in the female germline functioning as a general deleter to remove exons 2-5, thus creating a null allele. (J:131055)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 10 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eomes Mutation:  41 strains or lines available
References
Original:  J:131055 Arnold SJ, et al., Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse. Development. 2008 Feb;135(3):501-11
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory