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Targeted Allele Detail
Symbol: Zbtb7btm1Tani
Name: zinc finger and BTB domain containing 7B; targeted mutation 1, Ichiro Taniuchi
MGI ID: MGI:3774002
Synonyms: Th-POKGFP, Th-POK-GFP
Gene: Zbtb7b  Location: Chr3:89377644-89393673 bp, - strand  Genetic Position: Chr3, 39.09 cM, cytoband A1-A2
Germline Transmission:  Earliest citation of germline transmission: J:131081
Parent Cell Line:  M1/M-1 (ES Cell)
Strain of Origin:  (129 x C57BL/6)F1
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe coding region was replaced with GFP and a floxed neo cassette. Transient expression of cre-recombinase removed the neo cassette leaving a single loxP site behind. (J:131081, J:141142)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Zbtb7b Mutation:  19 strains or lines available
Original:  J:131081 Setoguchi R, et al., Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development. Science. 2008 Feb 8;319(5864):822-5
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory