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Myocdtm1Msp
Targeted Allele Detail
Summary
Symbol: Myocdtm1Msp
Name: myocardin; targeted mutation 1, Michael S Parmacek
MGI ID: MGI:3773717
Gene: Myocd  Location: Chr11:65067387-65160815 bp, - strand  Genetic Position: Chr11, 40.42 cM
Alliance: Myocdtm1Msp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:131288
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA neo cassette with a 3' loxP site was inserted into intron 8 and an additional loxP site was inserted into intron 7. (J:131288)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myocd Mutation:  53 strains or lines available
References
Original:  J:131288 Huang J, et al., Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice. J Clin Invest. 2008 Feb;118(2):515-25
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory