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Rgs7bptm1Itl
Targeted Allele Detail
Summary
Symbol: Rgs7bptm1Itl
Name: regulator of G-protein signalling 7 binding protein; targeted mutation 1, inGenious Targeting Laboratory
MGI ID: MGI:3773065
Synonyms: R7BP-, R7BP KO, Rgs7bptm1Igl
Gene: Rgs7bp  Location: Chr13:105082412-105191438 bp, - strand  Genetic Position: Chr13, 56.9 cM, cytoband D1
Alliance: Rgs7bptm1Itl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130903
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe first two exons, including the start methionine, were replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis on brain extracts. (J:130903)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rgs7bp Mutation:  16 strains or lines available
References
Original:  J:130903 Anderson GR, et al., Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases. J Neurosci. 2007 Dec 19;27(51):14117-27
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory